Can I prevent a user from receiving any messages from the helpdesk?

The help desk system sends automated notifications to both agents and users.

A comprehensive list of these message types, along with instructions on how to disable them, can be found in this KB article.

However, some critical system messages cannot be disabled. To completely prevent a user or agent from receiving any email notifications from the help desk, navigate to Admin Settings > Contacts > Contact list. Locate the specific user and access their profile for editing by clicking the “role and permissions” tab. Within the edit options, you will find a checkbox labeled "Do not send emails to this user." Checking this box and saving the changes will ensure that the user receives no further communications from the help desk system.